Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka

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Figure 2.
Figure 2.

Schematic representation of the genomic organization of the sex chromosomes and LG9. Respectively, 383 kb, 194 kb, and 156 kb of the Y chromosome, X chromosome, and LG9 were analyzed. Boxes indicate the predicted coding sequences with similarity to known gene sequences. The red, green, yellow, and blue triangles above the Y-region indicate locations of the Y-specific 551-bp (551), 363-bp (363), 338-bp (338), and 335-bp (335) repeat elements, respectively. In the Y-chromosomal region, vdp, and two copies of Olaflnk, dmrt1bY, and KIAA0914 were identified. In the X-chromosomal BAC clone, pkd2, abcg2, vdp, Olaflnk, and KIAA0914 were identified. The first two genes were only found on the X-chromosomal BAC clone, since the corresponding region on the Y chromosome was not cloned. For gene symbols, see Table 1 and text. The four subregions, the Y-specific region (Y-specific), the region on the Y with identity to LG9 (Y-core), the region on the X corresponding to the sequenced Y chromosome (X-corresponding), and the region on LG9 with similarity to the Y-specific region (LG9-core) are indicated by two-headed arrows.

This Article

  1. Genome Res. 16: 815-826

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