Figure 5.
Improvement of gene prediction after pseudogene masking. (A) After masking out a pseudogene incorporated in the original gene model, the gene is predicted correctly. (B) A single gene model is split into two correct models after a pseudogene exon is masked. (C) Two gene models are merged into one correct model after masking the pseudogene in an intron of SLC16A1. UTRs are shown as thin blocks, coding exons as thicker blocks, and introns as lines. A gene is considered correctly predicted when the coding sequence is correct. This figure was modified from a screen shot of the UCSC Genome Browser at http://genome.ucsc.edu (Kent et al. 2002).
