A comprehensive catalog of human KRAB-associated zinc finger genes: Insights into the evolutionary history of a large family of transcriptional repressors

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Figure 2.
Figure 2.

Analysis of expression patterns for KRAB and SCAN-KRAB ZNF genes. Expression levels of members of the human KRAB and SCAN-KRAB genes are represented by red and green boxes (denoting higher and lower expression levels, respectively). Vertical columns of boxes represent different genes, and horizontal rows represent different tissues. We have grouped tissues into the following categories as labeled on the left of each panel: N indicates neural; I, immune; G, glandular; M, muscle; O, other organ; and R, reproductive. In panel A, the 211 analyzed genes are arranged in chromosomal order. Selected genomic clusters are indicated by colored boxes beneath the expression pattern. From left to right, the clusters are (as listed in Supplemental Table S1): 16p13.3, 16p11.2a, 19p13.2, 19p13.2-p13.13, 19q13.12-q13.13, 19q13.31, 19q13.41-q13.42, 19q13.43a, 19q13.43b, 6p22.1b, 7q22.1a, 7q36.1a, and 8q24.3c. In panel B, all selected expression profiles (described in text) have been clustered based on expression pattern similarity. Colored hash marks above the expression profiles indicate the chromosomal cluster from panel A with which each profile corresponds.

This Article

  1. Genome Res. 16: 669-677

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