Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome

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Figure 4.
Figure 4.

Most E2F1-binding sites are found in both HeLa and MCF7 cells. (A) Raw array data (one array for each cell type shown) and predicted E2F1-binding sites (L1) from ENr324 (chrX) in HeLa and MCF7 cells. Predicted sites (indicated as HeLa TFBS and MCF7 TFBS) are the results of using our standard analysis approach on three arrays from each cell type (see Results). (B) Pie chart showing that 75% of MCF7 sites overlap a HeLa site. (TFBS) Transcription factor binding site.

This Article

  1. Genome Res. 16: 595-605

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