A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications

Click on image to view larger version.

Table 2

Distribution of exons by EST, known genes and RefSeq genes

Click on table to view larger version.

Table 2

Nonredundant exon clusters of 2,216,993 spliced EST (best placement), 36,164 known genes, and 22,933 RefSeq genes that have intron–exon structures are placed in either duplication or unique regions in the human genome. Each transcription unit was only counted once in this analysis. The duplicate and unique regions in the human genome (May 2004) correspond to 153.99 and 2712 Mb, respectively, while the transcribed portions of the duplicate and unique regions are 76.78/1328.4 Mb in ESTs, 28.56/871.22 Mb in known genes, and 24.63/847.85 Mb in RefSeq genes.

This Article

  1. Published in Advance April 10, 2006, doi: 10.1101/gr.4949406 Genome Res. 16: 576-583

Preprint Server



Current Issue

  1. February 2026, 36 (2)
  1. Current Issue
  1. Alert me to new issues of Genome Research