Figure 3.
Network neighborhoods of PF14_0123 and PF08_0086. Associations with known proteins suggest a strong role for PF14_0123 (A) in the protein-folding machinery, whereas PF08_0086 (B) is likely involved in protein folding and trafficking. PF08_0086 is also linked to an uncharacterized protein associated with splicing factors and RNA-binding proteins. Together, PF08_0086 and PF13_0138 are likely a part of a larger cellular system involving protein synthesis and transport. Links were visualized using Cytoscape (Shannon et al. 2003). (Link colors) Phase transitions; (White links) highest confidence subset (see Results and Fig. 4).
