Examples of primary sequence data generated by the hybridization of randomly amplified targets to RPM v.1 tiled probe sets. Clinical throat swab sample NHRC #7151 was found to contain an adenoviral coinfection (Fig. 2D), as hybridization to the HAdV-5 E1A tiled prototype sequence region resulted in the identification of HAdV-5 E1A (A), whereas the sequence generated via hybridization to the HAdV-7 E1A tiled prototype sequence region suggested the presence of HAdV-21 (B). (C) Amplicons generated from clinical throat swab sample NHRC #49110 hybridized to the influenza A virus (A/New Caledonia/20/99) hemagglutinin (H1) gene prototype sequence but were identified (via REPI analysis) as influenza A virus (A/Madrid/1082/2001) H1N1. (*) Single nucleotides that differentiate the experimental sequence from the tiled prototype sequence.
