Table 3.
Top ranking transcription factors predicted in cell proliferation-related genes
|
Accession |
Factor |
Consensus |
〈R-score 〉 |
P-value |
|---|---|---|---|---|
| M00185 | NF-Y | TRRCCAATSR | 2.975 | ∼0 |
| M00430 | E2F-1 | TTSGCGG | 1.911 | 0.0015 |
| MA0038 | Gfi-1 | AAATCACWGY | 1.82 | 0.002 |
| M00175 | AP-4 | RYCAGCTGYG | 1.65 | 0.0611 |
| M00007 | Elk-1 | AACMGGAAGT | 1.625 | 0.0935 |
| M00716 | ZF5 | GSGCGCGR | 1.551 | 0.1945 |
| M00773
|
c-Myb
|
GNCAGTT
|
1.546
|
0.1622
|
-
Primary cell cycle regulators. NF-Y, and E2F were accurately predicted as top ranking transcription factors. Other high scoring TFs predicted with higher P-values are likely to regulate a subset of these cell proliferation genes.
