Figure 3.
PAP's prediction of target genes of transcription factors is consistent with chromatin immunoprecipitation experiment data. Target genes of transcription factors HSF1, HNF1a, HNF4a, HNF6, and E2F4 were determined by previous chromatin immunoprecipitation experiments and were collected from the literature. The nonparametric Mann-Whitney U test was used to test whether these validated genes have higher scores in PAP's predictions. In each case, the Z score and the P-value were calculated.
