High-throughput DNA methylation profiling using universal bead arrays

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Figure 2.
Figure 2.

Methylation assay reproducibility and differential methylation detection. Comparison of methylation profiles between lung cancer and matching normal tissue. The β-value (i.e., the methylation ratio measured for all 1536 CpG sites) obtained from one replicate experiment is plotted against that obtained from another technical replicate experiment. The left and center panels show the reproducibility of replicated assays on DNAs derived from lung adenocarcinoma G12022 (center) and its matching normal tissue (left). The right panel shows the comparison between the normal and the matching adenocarcinoma samples.

This Article

  1. Published in Advance January 31, 2006, doi: 10.1101/gr.4410706 Genome Res. 16: 383-393

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