“Genome design” model: Evidence from conserved intronic sequence in human–mouse comparison

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Figure 5.
Figure 5.

The product of the conserved sequence fraction and the between-species identity of this fraction (which can be considered as the fraction of conserved nucleotides) in introns of genes expressed in different numbers of human tissues (means with LSD intervals). (A) without correction. (B) corrected for identity of human Alu repeats and intron GC content, using the general linear model (GLM). (Only introns containing Alu repeats were taken in the latter case.) For the effect of the number of tissues in the GLM, P <10–8.

This Article

  1. Genome Res. 16: 347-354

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