Table 5.
Differentially expressed exonic SNPs regulated by variants in linkage disequilibrium
|
No. of heterozygous samples (from total of 12 individuals) |
No. of differentially expressed SNPs (allele ratio ≥1.3 in all heterozygous samples)a |
Exonic SNPs favoring expression of one alleleb(not imprinted) |
||
|---|---|---|---|---|
| No. observed |
No. expected by chance |
|||
| 3 | 34 | 18 | 8.50 | |
| 4 | 12 | 6 | 1.50 | |
| 5 | 7 | 3 | 0.44 | |
| 6 | 3 | 3 | 0.09 | |
| 7 | 0 | 0 | 0.00 | |
| 8 | 1 | 1 | 0.01 | |
| Total
|
57
|
31c
|
11.54
|
|
-
↵a Allele ratio ≥1.5 in at least one sample, allele ratio ≥1.3 in all heterozygous samples.
-
↵b Exonic SNPs for which the same allele is expressed higher in each of the heterozygous samples, excluding the three genes we consider likely to be regulated by imprinting.
-
↵c The 31 genes containing these 31 exonic SNPs are listed in Supplemental Table 4.
