Logistic regression protects against population structure in genetic association studies

Table 9.

Empirical power and total number of false positives generated by each method over 50 simulated data sets simulated under Scenario 2 but with 201 genes (410 SNPs)


Scenario 2: Additional null genes

CHISQ
GC
SLR
BLR
STR2
AM2
All SNPs included
   Power (%) 94 94 94 94 94 94
   Total no. false +ve 9 3 1 4 4 3
Causal SNP excluded
   Power (%) 72 68 68 72 74 76
   Total no. false +ve 9 3 1 3 2 4
Gene 1 excluded
   Total no. false +ve
9
3
2
6
3
4

This Article

  1. Genome Res. 16: 290-296

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