Logistic regression protects against population structure in genetic association studies

Table 3.

The percentage of the 50 data sets under each demographic scenario for which at least one of the 10 markers in gene 1 is significantly associated with disease



Power (%)
FST/struct
CHISQ
GC
SLR
BLR
STR2
AM2
(1) No structure 98 96 96 98 96 100
(2) Low/eq 100 100 100 98 92 100
(3) High/eq 92 90 90 88 88 90
(4) Low/un 94 94 94 94 86 94
(5) High/un 90 84 90 84 88 90
Average (SE)
95 (1.5)
93 (1.8)
94 (1.7)
92 (1.8)
90 (2.1)
95 (1.5)
  • The final row gives the mean over the first five rows, and its standard error (SE).

This Article

  1. Genome Res. 16: 290-296

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