Table 2.
Structural features of 33 characterized insertions
|
Structural feature |
Number observed |
|---|---|
| Full-length (∼6 kb) | 3 |
| 5′-truncated | 30 |
| Inverted | 17 |
| w/deletion | 14 |
| w/duplication | 1 |
| precise inversion | 2 |
| dual inversion | 2 |
| Extra 5′ nucleotides | 7 |
| 5′ boundary microhomologies | 22 |
| noninverted 5′ truncated L1s | 8/10 |
| inverted L1s | 14/15 |
| Inversion point microhomologies | 14/15 |
| Target site features | |
| deletion | 0 |
| precise integration | 3 |
| TSD ≤ 8 nt | 6 |
| TSD > 8 nt
|
24
|
