Functional genomics of membrane transporters in human populations

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Figure 4.
Figure 4.

Functional characterization of protein-altering variants of OAT3 (SLC22A8). Uptake of estrone sulfate and cimetidine in HEK-293 cells expressing reference OAT3 and OAT3 protein-altering variants. Uptake values are expressed as a percentage of reference OAT3. Each value represents mean ± SD from triplicate wells in a representative experiment. (*) The selectivity variant Ile305Phe.

This Article

  1. Published in Advance December 14, 2005, doi: 10.1101/gr.4356206 Genome Res. 16: 223-230

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