Table 1.
Duplicate pairs that have the highest alternative splicing divergence
|
Gene 1 |
AS forms of gene 1 |
Gene 2 |
AS forms of gene 2 |
Function of gene 1 |
Function of gene 2 |
P-value |
|---|---|---|---|---|---|---|
| NM_014364 | 2 | NM_002046 | 63 | GAPDH-2 | Glyceraldehyde-3-phosphate dehydrogenase, GAPDH | 0 |
| NM_000090 | 57 | NM_000393 | 2 | Collagen, type III, alpha 1 | Collagen, type V, alpha 2 | 1.5E – 14 |
| NM_080426 | 46 | NM_002073 | 0 | GNAS complex locus | G protein, alpha z polypeptide | 1.74E – 13 |
| NM_001658 | 39 | NM_001659 | 3 | ADP-ribosylation factor 1 | ADP-ribosylation factor 3 | 8.53E – 09 |
| NM_003970 | 38 | NM_003803 | 3 | Myomesin (M-protein) 2 | Myomesin 1 (skelemin) | 1.55E – 08 |
| NM_184041 | 43 | NM_005165 | 6 | Aldolase A | Aldolase C | 6.06E – 08 |
| NM_003127 | 30 | NM_003126 | 1 | α-spectrin, non-erythrocytic 1 | α-spectrin, erythrocytic 1 | 6.54E – 08 |
| NM_003971 | 3 | NM_033392 | 35 | Sperm associated antigen 9 | Protein kinase binding | 9.29E – 08 |
| NM_002473 | 30 | NM_005964 | 2 | Myosin, heavy polypeptide 9 | Myosin, heavy polypeptide 10 | 3.83E – 07 |
| NM_000188 | 23 | NM_000189 | 0 | Hexokinase 1 | Hexokinase 2 | 7.75E – 07 |
| NM_006087 | 1 | NM_178014 | 25 | Tubulin, beta 4 | Tubulin, beta polypeptide | 1.52E – 06 |
| NM_012268 | 25 | NM_138790 | 1 | Phospholipase D3 | Hydrolase activity | 1.52E – 06 |
| NM_016521 | 0 | NM_007111 | 21 | Transcription factor Dp-3 | Transcription factor Dp-1 | 2.86E – 06 |
| NM_018677 | 25 | NM_032501 | 2 | ACAS2 (ADP forming) | ACAS2 (AMP forming)-like | 7.62E – 06 |
| NM_002293 | 22 | NM_006059 | 1 | Laminin, gamma 1 | Laminin, gamma 3 | 9.72E – 06 |
| NM_006366 | 1 | NM_006367 | 22 | CAP, adenylate cyclase-associated protein, 2 | CAP, adenylate cyclase-associated protein 1 | 9.72E – 06 |
| NM_005061 | 0 | NM_000967 | 19 | Ribosomal protein L3-like | Ribosomal protein L3 | 1.05E – 05 |
| NM_015528 | 19 | NM_181710 | 0 | Ring finger protein 167 | Zinc and ring finger 4 | 1.05E – 05 |
| NM_001416 | 29 | NM_014740 | 4 | Eukaryotic translation initiation factor 4A, isoform 1 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 48 | 1.12E – 05 |
| NM_004739 | 3 | NM_004689 | 26 | MTA2 | Metastasis associated 1 | 1.7E – 05 |
| NM_017772 | 1 | NM_014346 | 21 | TBC1, member 22B | TBC1, member 22A | 1.79E – 05 |
| NM_002209 | 21 | NM_000887 | 1 | Integrin, alpha L | Integrin, alpha X | 1.79E – 05 |
| NM_000224 | 21 | NM_019010 | 1 | Keratin 18 | Keratin 20 | 1.79E – 05 |
| NM_004953 | 37 | NM_003760 | 9 | Eukaryotic translation initiation factor 4 gamma, 1 | Eukaryotic translation initiation factor 4 gamma, 3 | 3.08E – 05 |
| NM_182743 | 27 | NM_000637 | 4 | Thioredoxin reductase 1 | Glutathione reductase | 3.31E – 05 |
| NM_003380 | 31 | NM_001927 | 6 | Vimentin | Desmin | 3.51E – 05 |
| NM_021804 | 0 | NM_152831 | 17 | Angiotensin 1 converting enzyme (peptidyl-dipeptidase A) 2 | Angiotensin 1 converting enzyme (peptidyl-dipeptidase A) 1 | 3.81E – 05 |
| NM_198597 | 24 | NM_014822 | 3 | SEC24 related gene family, member C | SEC24 related gene family, member D | 5.19E – 05 |
| NM_152856 | 32 | NM_005778 | 7 | RNA binding motif protein 10 | RNA binding motif protein 5 | 5.61E – 05 |
| NM_019854 | 4 | NM_198319 | 26 | HMT1 hnRNP methyltransferase-like 4 | HMT1 hnRNP methyltransferase-like 2 | 5.65E – 05 |
| NM_006431 | 4 | NM_006429 | 26 | Chaperonin containing TCP1, subunit 2 (beta) | Chaperonin containing TCP1, subunit 7 (eta) | 5.65E – 05 |
| NM_006472 | 19 | NM_183376 | 1 | Thioredoxin interacting protein | Arrestin domain containing 4 | 6.06E – 05 |
| NM_021971 | 2 | NM_205847 | 21 | GDP-mannose pyrophosphorylase B | GDP-mannose pyrophosphorylase A | 7.83E – 05 |
| NM_012302 | 21 | NM_014921 | 2 | Latrophilin 2 | Latrophilin 1 | 7.83E – 05 |
| NM_054013 | 21 | NM_012214 | 2 | MGAT4B, transferase activity | MGAT4A, transferase activity | 7.83E – 05 |
| NM_000477
|
29
|
NM_001134
|
6
|
Albumin
|
α-fetoprotein
|
9.55E – 05
|
-
(AS) Alternative splice.
