A computational genomics approach to identify cis-regulatory modules from chromatin immunoprecipitation microarray data—A case study using E2F1

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Figure 7.
Figure 7.

E2F1 cooperates with and regulates other transcription factors. Shown is a schematic indicating the five different modules identified in this study using E2F1 ChIP–chip data. DAVID analysis of the OMPGProm database-identified promoters (Supplemental Table S3) revealed that transcription factors are a predominant category of target genes in all five E2F1 ChIPModules: Nucleic acid binding proteins constituted ∼20% of ChIPModule 1, 26% of ChIPModule 2, 10% of ChIPModule 3, 26% of ChIPModule 4, and 22% ChIPModule 5.

This Article

  1. Published in Advance October 19, 2006, doi: 10.1101/gr.5520206 Genome Res. 16: 1585-1595

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