A computational genomics approach to identify cis-regulatory modules from chromatin immunoprecipitation microarray data—A case study using E2F1

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Figure 4.
Figure 4.

ROC curves show that the ChIPModules approach, which has a true positive Sn value of 0.9 and a false positive 1 − Sp value of 0.1, performs better than using only the presence of an E2F1 PWM in a human promoter (Single) or the presence of a conserved E2F1 PWM in both human and mouse promoters (Conserved).

This Article

  1. Published in Advance October 19, 2006, doi: 10.1101/gr.5520206 Genome Res. 16: 1585-1595

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