Accurate and reliable high-throughput detection of copy number variation in the human genome

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Figure 3.
Figure 3.

Definition of CNV boundaries by CNVfinder. A CNV on chromosome 3 detected in three different hybridizations, demonstrating the consistent detection of the boundaries of CNV. First, clones above the dual 6×/4× SDe thresholds are called (red bars). Secondly, CNVfinder allows restricted extension of called regions using lower thresholds of 3×/1× SDe (blue bars, see Fig. 5 for details). The 6×/4× SDe thresholds are shown as dashed (6× SDe) and dotted (4× SDe) lines.

This Article

  1. Genome Res. 16: 1566-1574

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