Reconstructing contiguous regions of an ancestral genome

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Figure 2.
Figure 2.

(A) Nets. Human is the reference species. The line between intervals indicates that a genomic interval of zero or more unaligned bases exists in the nonreference species between the adjacent intervals (see text). (B) Orthology blocks. (C) Conserved segments, including outgroup nets. The order and orientation of OB2 and OB3 are conserved in all four species, so we merge them into a conserved segment.

This Article

  1. Genome Res. 16: 1557-1565

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