Origins and impact of constraints in evolution of gene families

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Figure 5.
Figure 5.

Shared transcription factors regulating pairs of paralogs from E-families and N-families. In E-families, 92% of the pairs had no TF-binding sites in common, whereas 29% of the pairs in N-families shared sites for at least two TFs (P < 1e-50). The distribution for N-families is characterized by a heavy tail with some pairs sharing as many as six TFs.

This Article

  1. Genome Res. 16: 1529-1536

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