Common fragile sites are conserved features of human and mouse chromosomes and relate to large active genes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

Frequencies of chromatin gaps (G) and double-strand breaks (DB) at different APC concentrations in (B) BALB/c and (C) C57BL/6 mouse splenocytes. The y-axis shows the mean numbers of G and DB per metaphase; for each strain and APC concentration, means ± standard errors were calculated from counts in 125 metaphases (five mice). Statistically significant differences (Mann- Whitney U-test, P < 0.05) between strains are indicated with asterisks (*). The numbers of induced G and DB are slightly higher in BALB/c compared to C57BL/6 cells.

This Article

  1. Published in Advance September 5, 2006, doi: 10.1101/gr.5335506 Genome Res. 16: 1222-1230

Preprint Server



Current Issue

  1. January 2026, 36 (1)
  1. Current Issue
  1. Alert me to new issues of Genome Research