Genomic organization of 17q compared to the orthologous Pan troglodytes region. (A) The genomic organization of the chromosome 17 centromeric region is depicted; α-satellite is colored as described in Figure 1. A 300-kb region containing monomeric α-satellite on human chromosome arm 17q was compared to the orthologous region of chimpanzee chromosome arm 19q. A VISTA alignment of the two regions is shown in pink. Percent identity between aligning sequences is indicated by the y-axis (50%-100% identical). α-Satellite (blue) and the gene WSB1 (purple) are shown. Areas of low percent identity between the two genomes can be explained by gaps in the chimpanzee assembly (black boxes) or sequences inserted in the human genome or deleted from the chimpanzee genome (colored boxes). (B) Mean percent identity ± one standard deviation for aligned α-satellite monomers from chimpanzees and humans.
