Table 2.

Maximum likelihood estimates of ω for different regions of L1

	ORF1 (5′) non-CC^a	Coiled-coil domain^b	ORF1 (5′)^c	ORF1 (3′)^d	ORF2
L1PA2 => L1PA1	0.329	NA	0.296	0.335	0.217
L1PA3 => L1PA2	0.161	0.740	0.445	0.083	0.277
L1PA4 => L1PA3	0.312	4.435	2.291	0.658	0.094
L1PA5 => L1PA4	0.926	∞	4.469	0.654	0.289
L1PA6 => L1PA5	0.430	2.906	0.809	0.116	0.159
L1PA7 => L1PA6	1.293	1.428	1.342	0.162	0.207
L1PA8 => L1PA7	0.901	0.872	0.843	0.221	0.373
L1PA8A => L1PA8	0.253	0.324	0.259	0.213	0.276
L1PA10 => L1PA8A	1.193	0.288	0.417	0.229	0.130
L1PA11 => L1PA10	0.166	1.307	0.738	0.400	0.183
L1PA13B => L1PA11	0.623	0.512	0.523	0.209	0.210
L1PA12 => L1PA13B	1.999	0.901	1.253	0.189	0.191
L1PA13A => L1PA12	0.154	0.282	0.242	0.191	0.270
L1PA14 => L1PA13A	0.357	0.410	0.384	0.258	0.181
L1PA15 => L1PA14	0.479	0.519	0.515	0.230	0.189
L1PA16 => L1PA15	0.637	0.150	0.266	0.164	0.236

The ratio ω was calculated using the method of Yang and Nielsen (2000). Values of ω > 0.8 are framed.
↵a This region corresponds to the 5′ end of ORF1 from position 13 to 141 of ORF1
↵b The coiled-coil domain ranges from position 142 to 396 of ORF1
↵c This region of ORF1 corresponds to the one identified by PLATO and ranges from position 13 to 396 of ORF1
↵d This region of ORF1 ranges from position 397 to the end of ORF1

Molecular evolution and tempo of amplification of human LINE-1 retrotransposons since the origin of primates