Systematic genome-wide annotation of spliceosomal proteins reveals differential gene family expansion

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Figure 4.
Figure 4.

Evolutionary relationship among the RNA-binding K-Homology (KH) domains of members of the family hnRNP-E/PCB for several metazoans, i.e., human (Hsap), mouse (Mmus), chicken (Ggal), Fugu (Frub), Ciona (Cint), fruit fly (Dmel), and C. elegans (Cele) (for simplicity only one rodent, one teleost, and one insect are shown). Amino-acid positions of each domain within the protein are also indicated in the domain identification. The unrooted Neighbor-Joining phylogenetic tree was generated using ClustalW (1000 bootstraps) based on amino-acid alignment generated by T-Coffee. Bootstrap values are shown. Branch lengths are scaled in arbitrary units.

This Article

  1. Genome Res. 16: 66-77

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