Categorization of the 109 Sanger chr22 genes without equivalents in our data set
|
Reason for lack of a known gene or TU corresponding to a Sanger gene |
No. of Sanger genes |
|---|---|
| Unknown; Sanger gene passes GSPS and LOCUS criteria | 11 |
| Sanger gene is transcriptionally silent,a but not in a recent duplication | 34 |
| Sanger gene is putatively transcriptionally silent,b and in a recent duplication | 35 |
| Sanger gene is homologous to immunoglobulin gene segments | 9 |
| Sanger gene is transcribed, but as an unspliced nonpolyadenylated singleton | 19 |
| Special case
|
1
|
-
↵a Transcriptionally silent: no public ESTs or flcDNAs overlap any exons of the Sanger gene model on the sense strand of that model
-
↵b Putatively transcriptionally silent: the Sanger gene model is in a recent paralogous segmental duplication. Some public ESTs and/or flcDNAs have high sense-strand homologies to the Sanger gene model. However, these ESTs/cDNAs match another copy of the duplicated region better than they match the copy containing the Sanger gene model being considered. Therefore, the Sanger model is most likely transcriptionally silent
