Fusion events tested by RT–PCR
|
Gene 1a |
Gene 2b |
Number of sequences supporting fusionc |
Upstream gene (WT) detectedd |
Fusion RNA detectede |
|---|---|---|---|---|
| NME1 | NME2 | 30 | + | + |
| NME2 | WDR50 | 1 | + | – |
| RBM14 | RBM4 | 20 | + | – |
| BCL2L2 | PABPN1 | 1 | + | + (Testis) |
| TMPRSS3 | TFF1 | 1 | + | – |
| CTBS | GNG5 | 15 | + | + |
| MAG | CD22 | 1 | + | – |
| PIR | FIGF | 1 | – | + (Brain) |
| SERPINA5 | SERPINA3 | 1 | + | – |
| RPL17 | LOC497661 | 1 | + | + |
| NM_003947 | NM_007064 | 2 | + | + |
| HOXC10 | HOXC5 | 1 | + | – |
| SPN | QPRT | 1 | + | + (Farage) |
| NM_033542 | NM_018478 | 9 | + | + |
| GIMAP1 | GIMAP5 | 1 | – | – |
| HIF1A | SNAPC1 | 1 | + | – |
| C1QA | C1QG | 1 | – | – |
| MIA | RAB4B | 1 | + | + |
| S100A3 | S100A4 | 1 | – | – |
| MUC1 | KRTCAP2 | 1 | + | – |
| PIP5K1A | PSMD4 | 0 | + | + Retrogene |
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+ TIC (HepG2)
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↵a Gene symbol of the upstream gene. RefSeq name appears where gene symbol is N/A
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↵b Gene symbol of the downstream gene
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↵c The number of fusion-supporting ESTs found by our computational search
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↵d RT–PCR validation of the existence of the wild-type upstream sequence (having the original termination point). In four of the 20 tested cases, the WT was not detected in the tissues we tested
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↵e RT–PCR validation of the fusion transcript between genes 1 and 2. In case the expression of the fusion was confined to a specific tissue, the tissue name is mentioned in parentheses. No tissue name is mentioned in cases where the expression of the fused transcript was detected in RNAs from multiple tissues
