Evolutionary mechanisms shaping the genomic structure of the Williams-Beuren syndrome chromosomal region at human 7q11.23

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

Phylogenetic trees based on the neighbor-joining method (nucleotide gamma: Tamura Nei) or Bayesian method. Subindexes c, m, t, and 7q22 refer to centromeric, medial, telomeric, and 7q22 chromosomal localization of the human PSVs, respectively. Number 1 refers to the copy more similar to the ancestral human gene, and number 2 to the other copy. (A) Neighbor-joining tree obtained for the STAG3 gene PCR product (BA/STAG3) including HSA, PTR, GGO, PPY, MFU, and PNU. Branch numbers refer to the neighbor-joining bootstrap values/clade credibility values for the Bayesian tree, which was of identical conformation. (B) Bayesian tree obtained for the Block C Large fragment, including HSA, PTR, and PNU. Branch values refer to the clade credibility values.

This Article

  1. Genome Res. 15: 1179-1188

Preprint Server