Figure 4.
Genomic organization and gene order in the different species by multicolor FISH. Interphase FISH with three probes: BAC RP11-421B22 (CALN1 locus, green), BAC RP11-622P13 (STX1A locus, red), and PAC RP4-665P05 (GTF2IRD1 locus, yellow) showed the relative organization of the two loci within the WBS critical region with respect to an outside gene. A regional inversion is found in all primates but macaque, whose genomic structure is therefore identical to that of baboon and mouse. The location of each probe with respect to the human and predicted macaque maps is shown at the top.
