Region-specific detection of neuroblastoma loss of heterozygosity at multiple loci simultaneously using a SNP-based tag-array platform

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Figure 4.
Figure 4.

Primary tumor data interrogating SNPs in the region of 1p and 11q23. Tumors 433 and 427 were interrogated for the seven commonly altered regions in neuroblastoma (NB) and compared to results from the corresponding constitutional DNAs. Blue circles and purple squares indicate homozygous SNPs, while green triangles indicate heterozygous SNPs. All heterozygous SNPs in the tumor sample, when compared to the normal sample, have been converted to hemizygous SNPs in both regions, thus showing LOH. Typing results (LOH/No LOH) for the seven different regions are listed on the far right.

This Article

  1. Genome Res. 15: 1168-1176

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