Estimating the tempo and mode of gene family evolution from comparative genomic data

Table 2.

List of the most significant gene families identified as unlikely under the BD model


Family name name

Family sizes in Newick notation

Predicted branch

Likelihood ratio
Stress response (15 (33 (24 (30 31)))) 1 6e6
Amino acid biosynthesis (3 (8 (6 (6 5)))) 1 36
PGM/PMM (1 (3 (3 (2 1)))) 1 9
Ribosomal L1 (1 (4 (1 (1 1)))) 2 3e3
Chaperone (1 (4 (2 (2 1)))) 2 47
α/β hydrolase (2 (2 (6 (2 2)))) 3 2e4
Dihydrouridine synthase (1 (1 (6 (1 1)))) 3 6e5
Trichothecene pump (5 (5 (7 (10 6)))) 4 6e3
RNA polymerase Rpb1 (4 (3 (5 (7 4)))) 4 1e3
Transposon (2 (8 (15 (34 83)))) 5 4e54
Helicase (1 (3 (3 (2 34)))) 5 1e39
Thiol oxidase (1 (1 (4 (2 3)))) 6 1e3
Leucine rich repeat (4 (3 (1 (2 1)))) 6 38
Flocculation (10 (6 (8 (11 14)))) 7 85
Transposon (17 (14 (15 (1 5)))) 7 6e10
Myosin
(5 (9 (9 (5 5))))
7
76
  • The first column gives the gene family name; the second column describes the gene family size among the five Saccharomyces species in Newick notation. The third column gives the branch that is predicted to be responsible for the overall low p-value of the family using the likelihood ratio test, and the fourth column gives the corresponding likelihood ratio. Newick numbers in bold indicate the branch identified.

This Article

  1. Genome Res. 15: 1153-1160

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