Gene-breaking: A new paradigm for human retrotransposon-mediated gene evolution

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Figure 4.
Figure 4.

The downstream product of the L1 ASP in Secernin 3 (NM_024583). The full gene product (top line) as well as the MAPS-terminated (line 2) and two ASP-derived (lines 3,4) products are shown; the ASP-derived product that we sequenced, in line 4, skips exon 6 of secernin 3, presumably due to splicing, whereas the database sequence contains exon 6 as well as the L1 sequence and part of exon 7. As in Figure 3, gray boxes and lines indicate the expected structure of the mRNAs shown; these sequences are inferred from the known sequence of the full-length mRNA.

This Article

  1. Genome Res. 15: 1073-1078

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