Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

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Figure 5.
Figure 5.

Extreme conservation at the 3′ end of the ELAVL4 (HuD) gene, an RNA-binding gene associated with paraneoplastic encephalomyelitis sensory neuropathy and homologous to Drosophila genes with established roles in neurogenesis and sex determination (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM). The 3117-bp conserved element that overlaps the 3′ UTR of this gene (arrow) is the fifth highest scoring conserved element in the human genome (log odds score 2475). Several conserved elements in introns are also visible.

This Article

  1. Genome Res. 15: 1034-1050

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