Table 1.
Expected frequency distribution of neutral variants in humans
|
Frequency range |
Expected fraction of neutral variants |
|---|---|
| <0.01 | 0.54 |
| 0.01–0.10 | 0.23 |
| 0.10–0.50 | 0.16 |
| 0.50–0.90 | 0.06 |
| >0.90
|
0.01
|
-
The probability that a neutral variant has frequency between a and b is approximately C-1ln(b/a), where C is half the mean time to fixation or loss (Ewens 1974), which we have estimated as 10 for humans. Frequency of the most recently arisen allele (the derived allele) is used.
