Identification of a missense mutation in the bovine ABCG2 gene with a major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle

Table 4.

Variance components and marker substitution effects from REML analysis of the sire evaluations



Trait

Kg milk
Kg fat
Kg protein
% Fat
% Protein
Variance components
   ABCG2(2) 86,640 13.0 12.9 0.0145 0.0128
   Polygenic 272,720 553.0 286.4 0.0481 0.0101
   Residual 84,504 1.2 0.1 0.0005 0.0001
Substitution effectsa
   ABCG2(2) 520 6.4 6.3 0.213 0.200
Variance components
   ABCG2(2) 103,080 2.71 5.1 0.0135 0.0129
   SPP1(2) 0 0.0 0.0 0.0000 0.0000
   Polygenic 270,550 563.0 289.1 0.0480 0.0096
   Residual 77,542 1.6 0.0 0.0000 0.0007
Substitution effectsa
   ABCG2(2) 568 2.9 4.0 0.213 0.201
   SPP1(2) 0 0.0 0.0 0.000 0.000
Variance components
   ABCG2(2) 161,952 0 0 0.0158 0.0153
   HERC6 15,178 20.6 22.6 0 0
   Polygenic 267,670 521.3 282.3 0.0456 0.0093
   Residual 86,103 1.0 0.1 0 0.0002
Substitution effectsa
   ABCG2(2) 711 0 0 0.222 0.219
   HERC6 218 8.0 8.4 0 0
Variance components
   ABCG2(2) 85,277 4.7 8.4 0.0133 0.0134
   LAP3 2697 9.2 7.1 0 0
   Polygenic 291,069 556.9 286.0 0.0493 0.0094
   Residual 77,829 1.0 0 0 0
Substitution effectsa
   ABCG2(2) 516 3.8 5.1 0.204 0.205
   LAP3
92
5.4
4.7
0
0
  • a Computed as described in the Methods section

This Article

  1. Genome Res. 15: 936-944

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