Table 1.
Significantly overrepresented homotypic motif pairs (anchor = neighbora)
|
Anchor motif |
Binding factor |
Window size, bp |
NSb |
PECc |
|---|---|---|---|---|
| M00017 | ATF | 50 | 4.5E-5 | Nd |
| M00039 | CREB | 50 | 2.2E-4 | Nd |
| M00119 | Max | 50 | 3.4E-5 | Nd |
| M00121 | USF | 50 | 2.6E-13 | 2.5E-6 |
| M00123 | c-Myc/Max | 50 | 1.6E-3 | 1.3E-6 |
| M00178 | CREB | 50 | 9.7E-8 | Nd |
| M00185 | NF-Y | 50 | 3.0E-59 | 9.3E-7 |
| M00209 | NF-Y | 50 | 3.1E-24 | 1.0E-6 |
| M00210 | Oct-x | 50 | 1.6E-6 | 1.3E-6 |
| M00220 | SREBP-1 | 50 | 6.6E-13 | 6.9E-6 |
| M00236 | Arnt | 50 | 3.1E-7 | Nd |
| M00287 | NF-Y | 50 | 2.7E-12 | 9.8E-7 |
| M00338 | ATF | 50 | 3.9E-5 | Nd |
| M00341 | GABP | 50 | 1.6E-12 | 9.1E-7 |
| M00342 | Oct-1 | 50 | 1.6E-8 | Nd |
| M00491 | MAZR | 50 | 4.6E-42 | Nd |
| M00615 | c-Myc/Max | 50 | 1.4E-10 | Nd |
| M00652 | Nrf-1 | 50 | 1.3E-12 | Nd |
| M00678 | Tel-2 | 50 | 1.6E-12 | 9.6E-7 |
| M00687 | α-CP1 | 50 | 8.4E-13 | 1.0E-6 |
| M00121 | USF | 100 | 3.0E-8 | 1.1E-6 |
| M00185 | NF-Y | 100 | 3.5E-50 | 9.9E-7 |
| M00209 | NF-Y | 100 | 2.2E-45 | 1.0E-6 |
| M00220 | SREBP-1 | 100 | 3.7E-9 | 1.0E-6 |
| M00236 | Arnt | 100 | 1.5E-4 | Nd |
| M00287 | NF-Y | 100 | 3.0E-12 | 9.8E-7 |
| M00341 | GABP | 100 | 7.6E-13 | 1.1E-6 |
| M00342 | Oct-1 | 100 | 2.9E-8 | Nd |
| M00491 | MAZR | 100 | 4.3E-5 | Nd |
| M00539 | Arnt | 100 | 5.3E-8 | Nd |
| M00615 | c-Myc/Max | 100 | 5.8E-9 | 1.5E-6 |
| M00652 | Nrf-1 | 100 | 1.3E-12 | 1.0E-6 |
| M00678 | Tel-2 | 100 | 2.4E-11 | 1.0E-6 |
| M00687
|
α-CP1
|
100
|
1.2E-12
|
1.0E-6
|
-
↵a CompareACE > 0.85.
-
↵b Neighbor specificity score.
-
↵c P-value on the hypothesis that the genes with motif combination are equally or less correlated in expression than either anchor or neighborcontaining genes without the combination.
-
↵d Not statistically significant after taking into account multiple testing (see text for details).
