Discovering functional transcription-factor combinations in the human cell cycle

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Figure 3.Figure 3.
Figure 3.

A functional combination discovered from our analysis involving NF-Y binding site and a significantly enriched neighbor motif within 50 bp downstream. (A) Sequence logo of the neighbor motif, produced by the World Wide Web service at http://www.bio.cam.ac.uk/cgi-bin/seqlogo/logo.cgi. The height of each letter is proportional to its frequency of occurrence in the binding-site matrix, times the information content at each position. (B) The expression profiles of genes containing the NF-Y neighbor-motif combination. The blue lines represent expression profiles of individual genes, and the red line represents mean expression profile of the group. (C) The expression profiles of genes containing NF-Y motif, but without neighbor motif within 50 bp downstream. (D) The expression profile of genes containing the neighbor motif, but without NF-Y within 50 bp upstream.

This Article

  1. Genome Res. 15: 848-855

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