Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism

Table 2.

Comparison of the genome characteristics and the in silico metabolic networks of prokaryotic and eukaryotic species



Prokaryotes

Eukaryotes

S. coelicolor A3(2)
E. colia
H. influenzaeb
H. pyloric
S. cerevisiaed
Genome characteristics
Genome length (bp) 8,667,507 4,639,221 1,830,135 1,667,867 12,175,026
G+C content 72% 51% 38% 39% 40%
ORF 7825 4288 1743 1590 6281
Assigned function 5492 2656 1011 1091 4379
No assigned function 2333 1632 732 499 1902
In silico metabolic network characteristics
Total reactions (unique) 971 (700) 931 (931) 461 381 1175 (842)
Biochemical conversions 819 767 826
Transport 152 164 349
Reactions with ORF (% of total reactions) 764 (79%) 873 (94%) 412 (89%) 272 (71%) 1035 (88%)
Metabolites 500 625 367 332 584
ORF (% of ORFs with assigned function)
711 (13%)
904 (34%)
400 (40%)
290 (27%)
708 (16%)

This Article

  1. Genome Res. 15: 820-829

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