Identification of functional transcription factor binding sites using closely related Saccharomyces species

Table 2.

Binding site conservation for five known transcription factors


Name

Consensus

S. cer. sitesa

S. par. sitesa

S. mik. sitesa

Conserved sitesb

Percent conservedc

P(cons)d

False discovery rate
ABF1 RTCRYNNNNNACG 671 670 666 470 70.0 0.017 0.024
GAL4 CGGNNNNNNNNNNNCCG 144 152 134 21 14.6 0.022 0.153
MCM1 CCNNNWWRGG 963 1019 911 194 20.1 0.023 0.112
NDT80 YGNCACAAAW 141 133 141 59 41.8 0.006 0.015
UME6
TSGGCGGCTAW
82
86
86
63
76.8
0.002
0.003
  • a The number of matches to the PWM in each genome.

  • b The number of conserved matches to the PWM.

  • c The percentage of matches to the PWM that are conserved.

  • d The probability of motif conservation.

This Article

  1. Genome Res. 15: 701-709

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