The linkage disequilibrium maps of three human chromosomes across four populations reflect their demographic history and a common underlying recombination pattern

Table 5.

Chromosome-wide SNP and LD summary statistics


Population

Statistic

Chr 6

Chr 21

Chr 22
African-American No. of SNPs 9129 3418 3688
SNP spacing on covered segments (kb)a
Mean 10.1 7.9 7.3
Median 6.9 4.5 4
Minor allele frequency
Mean 0.29 0.3 0.29
Median 0.28 0.3 0.29
Decay of LD (kb)
|D′| half length 28.9 19 18.2
r2 half length 16.4 11.8 9.9
Swept radius 41 22.1 21.8
Caucasian No. of SNPs 9274 3551 3931
SNP spacing on covered segments (kb)a
Mean 9.9 7.6 7
Median 6.7 4.1 3.7
Minor allele frequency
Mean 0.31 0.31 0.31
Median 0.31 0.32 0.32
Decay of LD (kb)
|D′| half length 46 29.5 29.3
r2 half length 26.7 19.2 19.3
Swept radius 56.3 31.2 30.9
Chinese No. of SNPs 10,916 3567 3496
SNP spacing on covered segments (kb)a
Mean 11.7 8.2 7.7
Median 8.3 5.8 4.7
Minor allele frequency
Mean 0.3 0.3 0.3
Median 0.3 0.3 0.3
Decay of LD (kb)
|D′| half length 41.7 31.2 31.8
r2 half length 27.5 20.4 21.8
Swept radius 50.2 31.3 31.6
Japanese No. of SNPs 10,825 3536 3483
SNP spacing on covered segments (kb)a
Mean 11.8 8.3 7.8
Median 8.4 5.9 4.6
Minor allele frequency
Mean 0.3 0.3 0.31
Median 0.31 0.31 0.3
Decay of LD (kb)
|D′| half length 44 32.8 34
r2 half length 28.9 21.1 21.1

Swept radius
53.1
34.6
33
  • a Covered segments are defined as intervals where inter-SNP distances are ≤50 Kb

This Article

  1. Genome Res. 15: 454-462

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