Protein interaction mapping: A Drosophila case study

Table 3.

Distribution of domains in the fly proteome, interacting proteins, and SID




Drosophila proteome

Proteins in data set

SID in data set
With TM 20% 205 12%a 105 6%a,b
With SP 21% 247 14%a 85 5%a,b
With InterPro domain 78% 1258 73%a 1024 62%a,b
Total

1727

1651

  • Transmembrane (TM) segments (Krogh et al. 2001), signal peptide (SP) (Nielsen et al. 1997), and InterPro domains (Ashburner and Lewis 2002) were predicted from the primary sequences of the proteins in the present data set and the complete Drosophila proteome. Mapped domains were then compared with the SID.

  • a Significantly different (p < 0.05) from representation in Drosophila proteome.

  • b Significantly different (p < 0.05) from representation in interacting proteins.

This Article

  1. Genome Res. 15: 376-384

Preprint Server