Naturally occurring antisense: Transcriptional leakage or real overlap?

Table 3.

Genomic distances of gene pairs with human-mouse linkage




Antisensea

Same-strand

Totalb
Distancec Human Mouse Human Mouse Human Mouse
Average (kb) 4.1 4.5 115 104 110 100
Median (kb) 1.4 1.5 28 22 26 21
Average difference (kb) −0.4 11 10
# of pairs
135
1908
3681
  • a Pairs of genes that were identified as antisense both in the human and the mouse genomes.

  • b 4036 pairs of consecutive genes that maintain the same gene order and orientation in both human and mouse were analyzed. Pairs that show antisense overlap in only one organism were discarded, resulting in a final set of 3681 pairs.

  • c Distances were calculated between the coding sequence (CDS) coordinates of each pair of genes on each genome (see Methods).

This Article

  1. Genome Res. 15: 364-368

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