ProbCons: Probabilistic consistency-based multiple sequence alignment

Table 4.

Significance test for differences in PREFAB performance




DIALIGN

CLUSTALW

T-Coffee

MUSCLE

MAFFT

ProbCons

ProbCons-ext
DIALIGN −1.06 × 10−9 − <10−10 − <10−10 − <10−10 − <10−10 − <10−10
CLUSTALW − <10−10 − <10−10 − <10−10 − <10−10 − <10−10
T-Coffee − <10−10 − <10−10 − <10−10 − <10−10
MUSCLE +2.3 × 10−9 − <10−10 − <10−10
MAFFT − <10−10 − <10−10
ProbCons






−0.031
  • Entries show the p-value indicating the significance of a difference in performence between two alignment methods as measured using a Friedman rank test. Values were calculated using Q (SP) scores on all alignments. (+) Method on the left had lower average rank (better performance); (−) Method on the left had higher average rank (worse performance); parentheses denote (nonsignificant) p-values >0.05.

This Article

  1. Genome Res. 15: 330-340

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