Phenotypic trends in the ovary-enriched genes across different phyla. Genes were classified as “All Eukaryotic” if a homolog was identified in yeast, as “Multicellular” if a homolog was identified in either fly, human, and/or Arabidopsis (only a handful of genes were shared between C. elegans and Arabidopsis but not fly or human) and was not found in yeast, or as “Worm” if no homolog was identified in any of these species. Eukaryotic genes are significantly (P < 0.001, hypergeometric probability test) overrepresented in MS and EL phenotypic categories and significantly underrepresented in the NELD category. Conversely, worm-specific genes are significantly overrepresented in the NELD category and significantly underrepresented in MS and EL categories.
