A high-resolution multistrain haplotype analysis of laboratory mouse genome reveals three distinctive genetic variation patterns

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Figure 4.
Figure 4.

Resequencing results of the 44 genomic segments at 21 genomic loci. The y-axis shows the SNP density (number of the SNPs per kilobase) derived from resequencing that represents variations in 13 laboratory inbred strains, intra-subspecies variations in wild-derived inbred strains of domesticus subspecies (intra-domesticus), and inter-subspecies variations between domesticus and musculus subspecies (domesticus/musculus). At the x-axis, each segment is labeled by its genome locus; multiple segments selected from the same locus are labeled with the same name. Genomic loci are shown in the same numeric order as in Supplemental Table S4. A locus is underlined with a solid line if it is a large haplotype block, a dotted line if it is a fragmented block; the line color indicates whether the variations in the laboratory inbred strains arise from intra-subspecies variations in domesticus (blue), inter-subspecies variations between domesticus and molossinus (red), domesticus versus haplotypes only found in laboratory inbred strains (brown), or molossinus versus haplotypes only found in laboratory inbred strains (green).

This Article

  1. Genome Res. 15: 241-249

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