Gene conversion and evolution of Xq28 duplicons involved in recurring inversions causing severe hemophilia A

Table 6.

Haplotypes of two distal int22h sequences

49
880
1007
1168
1477
1567
4069
4094
4302
4340
4341
4350
4619
5076
5880
7652
8444
8449
8509
8802-8850
No. observed
Chimpanzee
T
 G
 G
 A
 C
 A
 C
 G
 C
 G
 G
 T
 T
 A
 G
 A
 —
—
—
Y
 1
Haplotype number
1 C G A C A G N 4
2 C G A G N 9
3 C G C A G N 5
4 C G G N 1
5 C G C G N 3
6 C G C G N 1
7 C A C A G N 1
8 C C A G N 1
9 C A G A N 1
10 C A G C A N 1
11 C A G A G N 2
12 C A G C A G N 4
13 C A G C G A G N 1
14 C G T G N 1
15 C G C G A G N 2
16 C G G A G N 1
17 A G G C N 1
18 A G G G C G A Y 2
19 A A G G G C G A Y 1
20 A G G G G C G G A Y 1
21 A G G G C G G A Y 1
22 A G G G C G G A Y 1
23 A G G G C G A N 1
24 A G G G C G T A N 1
25 A G G G C G T A Y 5
26 A G G C G G T G A Y 1
27
A
G
G
G
C
G
G
T
G
A
Y
1

  • Distal int22h human nucleotide number at sites of polymorphism is on the top. Empty spaces indicate that base is identical to that of chimpanzee's sequence or to bases found in the reference human DNA and absent in chimpanzee (italics). Novel alleles are in upper case. Column 8802-8850 shows presence (Y) or absence (N) of polymorphic tandem duplication.

This Article

  1. Genome Res. 15: 214-223

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