
(A) DAPI-banded metaphase spread from a clinically normal male dog. Note that the karyotype (2n = 78) comprises 38 pairs of acrocentric autosomes, a large submetacentric X chromosome, and a small metacentric Y chromosome. (B) Typical DAPI-banded metaphase preparation of a cell derived from canine osteosarcoma case OS-a. This tumor has a consistent chromosome number of 34 (30/30 cells) and presented with a complex karyotype comprising multiple metacentric chromosomes.











