Short interspersed elements (SINEs) are a major source of canine genomic diversity

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Figure 1.
Figure 1.

Construction of libraries that are enriched for SINEC_Cf elements and flanking sequence. (A) Genomic DNA is cleaved with the frequently cutting restriction enzyme, NlaIII. (B) The cleaved fragments are self-ligated. (C) The circularized products are subjected to PCR using SINEC_Cf-specific primers. (D) The linear products are size-selected and cloned in a plasmid vector. (E) Inserts are sequenced with a vector-specific primer.

This Article

  1. Genome Res. 15: 1798-1808

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