Hotspots of mutation and breakage in dog and human chromosomes

Table 5.

Correlations (Spearman's ρ/P-value) of gene properties with increasing distance from centromeres or telomeres


Property

Human subtelomere

Dog subtelomere

Human pericentromere

Dog pericentromere
Ks –0.39/<2.2 × 10-16 –0.23/2.2 × 10-5 –0.02/0.34 –0.1/2.6 × 10-11
GC4D –0.27/<2.2 × 10-16 –0.18/4.8 × 10-3 0.06/1.0 × 10-4 –0.09/5.7 × 10-9
GC53
–0.38/<2.2 × 10-16
–0.27/2.7 × 10-5
–0.08/2.0 × 10-7
–0.14/<2.2 × 10-16
  • Correlations were calculated for D2 genes (unbinned) within 20 Mb of either a centromere or a telomere.

This Article

  1. Genome Res. 15: 1787-1797

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